A single percentage tells you very little. What matters is the number that applies to you — your age, your diagnosis, your embryos. At IRFC, we believe honest, personalized probability estimates build more trust than headline statistics.
A clinic with a 45% overall rate may serve mostly younger patients. A clinic with a 38% rate may specialize in complex, high-age cases. Overall averages conceal more than they reveal.
The laboratory environment — temperature, oxygen levels, culture media, embryologist expertise — has a profound effect on embryo development. Two clinics with identical patients can produce very different embryos.
IVF for unexplained infertility has a very different success profile than IVF for severe diminished ovarian reserve. The right number is the one calculated for your specific clinical picture.
The table below shows national average live birth rates per retrieval cycle from SART (Society for Assisted Reproductive Technology) data — using a patient's own eggs, all diagnoses combined. These are reference benchmarks, not IRFC-specific figures. Your physician will discuss your individual probability at consultation.
| Age Range | National Avg. (Live Birth / Retrieval) | Clinical Context |
|---|---|---|
| Under 35 | 47% | Egg quality and quantity are at their peak. Most patients in this group respond well to stimulation. |
| 35 – 37 | 38% | Strong outcomes remain achievable. Personalized protocols and lab quality make a measurable difference. |
| 38 – 40 | 25% | PGT-A genetic testing is often recommended to identify the strongest embryos and reduce miscarriage risk. |
| 41 – 42 | 13% | Multiple cycles or donor egg IVF significantly improve the probability of success for patients in this range. |
| Over 42 | 5% | Donor egg IVF offers success rates equivalent to the donor's age — typically 50%+. Many patients find this path profoundly meaningful. |
Source: SART national averages, own-egg IVF cycles. Individual outcomes vary by diagnosis, protocol, laboratory quality, and embryo genetics. Data reflects approximate recent national averages and is provided for educational context only.
Egg quality and quantity are at their peak. Most patients in this group respond well to stimulation.
Strong outcomes remain achievable. Personalized protocols and lab quality make a measurable difference.
PGT-A genetic testing is often recommended to identify the strongest embryos and reduce miscarriage risk.
Multiple cycles or donor egg IVF significantly improve the probability of success for patients in this range.
Donor egg IVF offers success rates equivalent to the donor's age — typically 50%+. Many patients find this path profoundly meaningful.
Source: SART national averages, own-egg IVF. Individual outcomes vary. Provided for educational context only.
A Different Path
For patients with diminished ovarian reserve or prior IVF failures, donor egg IVF resets the success probability to the donor's age group — typically 50–60% per transfer, regardless of recipient age. Many patients find that this path, though different from what they imagined, is the most direct route to the family they've always wanted.
These distinctions are independently verified and rooted in clinical outcomes — not self-reported marketing claims.
US IVF Laboratory
SART — 2016
The IRFC embryology team, led by Dr. Yufen Xie, achieved the highest IVF success rates in the United States in 2016. This ranking is based on verified CDC-reported outcomes submitted to SART.
Kaiser Permanente Center of Excellence
Southern California Designation
One of the most rigorous independent quality designations in reproductive medicine. Requires consistently exceeding benchmarks for clinical outcomes, safety record, and patient experience standards.
Certified Laboratory
CAP / CLIA Accreditation
Our IVF laboratory meets the College of American Pathologists' highest standards for quality management, personnel qualifications, and procedural accuracy — the same standard applied to the best hospital labs in the country.
Fairfax EggBank Production Facility
Donor Egg Program
IRFC is one of the largest Fairfax EggBank production facilities in the United States — a distinction reflecting consistent technical excellence in egg banking outcomes and laboratory precision.
Success in IVF is not determined by a single variable. Understanding what drives outcomes helps you ask better questions — and helps us build a better plan for you.
Discuss Your Specific CaseThe single most influential variable in IVF outcomes. Egg chromosome integrity declines with age — which is why your physician designs a stimulation protocol specifically calibrated to your ovarian reserve and history, not a generic one.
Embryos are extraordinarily sensitive to their culture environment. Temperature, oxygen levels, culture media composition, and handling practices all affect development. IRFC's CAP-certified laboratory and EmbryoScope+ continuous monitoring eliminate the environmental disruptions that compromise embryo quality in less rigorous settings.
The majority of IVF failures — and most miscarriages — are caused by chromosomally abnormal embryos. Preimplantation Genetic Testing (PGT-A) identifies euploid (chromosomally normal) embryos before transfer, significantly improving per-transfer success rates and reducing miscarriage risk.
Conditions such as diminished ovarian reserve, endometriosis, or severe male factor each require distinct clinical approaches. A physician who accurately diagnoses and adjusts protocol for your specific diagnosis achieves materially better outcomes than a one-size-fits-all approach.
Even a chromosomally perfect embryo requires the right uterine environment to implant. Your physician evaluates endometrial thickness, anatomy, and may recommend ERA (Endometrial Receptivity Analysis) or a mock cycle to optimize transfer timing for your body.
Laboratory equipment is not a marketing distinction — it is a clinical variable. Each of the following technologies is used for every IRFC patient, every cycle.
Continuous time-lapse monitoring means embryos are never removed from their optimal culture environment for observation. This eliminates temperature and oxygen disruptions that compromise development — and provides real-time data for selecting the strongest embryo.
Chromosomal screening before transfer identifies euploid embryos and eliminates the primary cause of IVF failure and miscarriage. For eligible patients, this translates directly into higher per-transfer live birth rates.
Automated electronic verification ensures biological samples are matched to the correct patient at every step of the IVF process — an absolute prerequisite for the highest quality standard of care.
24/7 real-time cryogenic monitoring with RFID tracking ensures the integrity of frozen eggs and embryos throughout storage — protecting your investment and your future.
If you have a question not covered here, your first consultation is the best place to ask. You'll speak directly with a physician — not a coordinator.
Book a ConsultationBecause a single percentage without context is, at best, incomplete — and at worst, misleading. A 50% rate for a 28-year-old with unexplained infertility is very different from a 50% rate for a 41-year-old with diminished ovarian reserve. The number that matters is yours. We discuss your personalized probability honestly at your first consultation.
US fertility clinics that perform ART cycles submit annual outcome data to the CDC. You can search the National ART Surveillance System (NASS) database at cdc.gov/art to compare reported outcomes across clinics, including IRFC. We encourage you to review this data and bring your questions to your consultation.
Your physician will review your complete history, bloodwork, ultrasound findings, and diagnosis before providing an honest, individualized estimate. Key inputs include your age, ovarian reserve (AMH and antral follicle count), uterine anatomy, partner's semen parameters, and any underlying conditions. We do not offer false hope — and we do not give up easily.
PGT-A improves the per-transfer live birth rate by ensuring only chromosomally normal (euploid) embryos are transferred. For patients over 35, or those with prior unexplained IVF failures, this can meaningfully reduce miscarriage risk and improve confidence in each transfer. Whether PGT-A is right for your situation is a discussion for your physician — it is not appropriate for every patient.
There is no universal answer, and anyone who gives you one is guessing. Some patients succeed on their first cycle; others benefit from two or three. Your physician will discuss the cumulative probability of success across multiple cycles based on your specific profile. Our financial coordinator can help you plan for different scenarios so cost is never a surprise.
Yes — significantly. Donor egg IVF success rates are primarily determined by the egg donor's age, not the recipient's. This means a 44-year-old patient using eggs from a 26-year-old donor can achieve success rates comparable to a 26-year-old patient using her own eggs — typically 50–60% per transfer. For patients with severely diminished ovarian reserve or prior IVF failures, donor egg IVF is often the most direct path to a healthy pregnancy.
Our physicians will review your history, explain your realistic probability of success, and design a plan built around your specific situation — not a generic protocol.
Telehealth available. Telehealth available for out-of-area and international patients.
